James L. Gleason
Professor
Organic Chemistry

email: jim.gleason@mcgill.ca
lab phone: 514-398-6225
Office: 309A, Otto Maass Chemistry Building

Department of Chemistry
McGill University
801 Sherbrooke St. West
Montreal, QC
H3A 0B8



 

 
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Recent Group News As of Oct 2024 - Follow us on BlueSky for recent group news. Our Twitter feed has been permanently closed. As of Sept 2022 - follow us on Twitter for more recent group news. 1 Sept 2022 Welcome to new graduate students Vanessa Watts and Spencer Petras, along with
 undergraduate researchers Sean Elliot and Abigail Robson 18 July 2022 Congratulations to Ryan Barrett on defending his Ph.D. Thesis. Ryan will be doing a posdoc with Chris Vanderwal at U.C. Irvine 30 June 2022 Congratulations to Josie Warnica on a successful Ph.D. defense. Josie will be doing a posdoc with Vy Dong at U.C. Irvine 7 June 2022 Our latest paper on the cycloadditions of heptafulvalene, and how they aren’t antarafacial as predicted 50 years ago, is out. Congrats to Anthony Izzotti 25 April 2022 Our latest paper on vitamin D receptor agonist/HDACi hybrids is out. Congrats to Ali
 Mansour and David Scarlata 22 March 2022 Our paper on the synthesis of 4-oxoisotaxodione is out. Congrats to Sam Plamondon 25 Feb 2022 Congratulations to Sam Plamondon for successfully defending his Ph.D. thesis. Sam will be working at Ventus Therapeutics. 9 Nov 2021 Our paper on antiandrogen/HDACi hybrids is out. Congratulations to Ryan 1 Nov 2021 Jim promoted to Full Professor 30 Aug 2021 Congratulations to Sam Plamondon for receiving a Paraza-Corialis Prize (Bronze) for his talk at the CSC-IUPAC conference 21 July 2021 Our paper on incorporating cation–π stabilization in organocatalysts is published in Can J. Chem. Congratulations to Josie. 26 Oct 2020 Congratulations to Adam Elmehriki on defending his Ph.D. thesis. Adam is doing a postdoc with Varinder Aggarwal (Bristol) 31 Aug 2020 Our joint paper with Ken Houk on the mechanism of the organocatalytic Cope is published
 in J. Am. Chem. Soc. Congratulations to June. 20 Aug 2020 Welcome to new graduate students Amelia Caza and Angela Novakovic 15 May 2020 After a 2-month halt due to COVID-19, we are cleared to run at 40% capacity 4 May 2020 Welcome to Andrew Little who will be doing an NSERC USRA project 30 April 2020 Congratulations to Yufei Wang on successful submission of her M.Sc. thesis. Yufei will work short term at Intellisyn before beginning her Ph.D. with Echavarren in Tarragona 19 March 2020 Our lab, along with all others at McGill, is shut down temporarily due to COVID-19 22 Jan 2020 New CIHR grant with Alyson Fournier, Tony Mittermaier and Nic Moitessier developing
 novel 14-3-3 PPI agonists. 21 Jan 2020 Welcome to undergraduate Melissa Lehnert. Melissa will be investigating higher-order 
 cycloadditions 9 Jan 2020 Welcome to new M.Sc. student Kellly Burchell-Reyes. Kelly will be working on the
 oxy-Cope reaction 22 Nov 2019 Our paper on spiroalkylation/alkylation applied to puraquinonic acid is published
 in Organic Letters. Congrats to Adam. 31 Oct 2019 Our paper on organocatalytic polyene cyclizations is published in Angewandte 
 Chemie. Congrats to Sam, Josie and Dainis. 26 Sept 2019 Welcome to new Ph.D. student Zhizhong Gao, who will be working on antiestrogens. Also, good luck to Adam Elmehriki who will be starting his postdoc with Varinder Aggarwal at U. Bristol (UK). 1 Sept 2019 Welcome to new Ph.D. student Anthony Izzotti (back after having spent summer 2018 with us). Anthony will be working on our organocatalysis projects. 13 Aug 2019 Our paper on aminoalkylation of [1.1.1]propellane is out. Congrats to Jon Hughes and David Scarlata 1 May 2019 Welcome to SURA undergraduate Maria Gorenflo 21 Nov 2018 Congratulations to Nicklas Häggman on a successful Ph.D. defense. 20 Nov 2018 Congratulations to Sam Plamondon on receiving an award for best oral presentation at the QOMSBOC conference in York, ON. 20 Sept 2018 Our paper on organocatalytic Diels-Alder reactions is out. Congrats to Nick, Benny
 June and Dainis 1 Sept 2018 Welcome to new M.Sc. student, Hayley McMillan. Hayley will be working on our organocatalysis projects. 17 July 2018 Our paper on tamoxifen/HDACi hybrids is out. Congrats to Anthony and Ben. 6 June 2018 Congratulations to Jon Hughes for winning the Udho-Parsini-Diwan Prize for the 
 best paper by a graduate student at McGill University for 2017. 2 May 2018 Welcome to USRA undergraduate Anthony Izzotti 1 May 2018 Congratulations to Yufei Wang on receiving an FRQNT fellowship. 8 February 2018 Congratulations to Jon Hughes for a successful Ph.D. defense. Good luck at Merck! 23 January 2018 New CIHR grant with Sylvie Mader: “Mechanisms of action of antiestrogens: towards improved treatment of relapse in ER+ breast cancer” 17 December 2017 Our full paper on the synthesis of virosaine is out. Congrats to Jon Hughes 30 August 2017 Welcome to new graduate students Donald Campbell, Hyun June Jun, David 
 Scarlata and Yufei Wang 25 August 2017 Our latest paper on vitamin D / HDACi hybrids is out. 15 August 2017 Congratulations to Jon Hughes and Nick Häggman for landing jobs at Merck 
 (Rahway) and Intellisyn 12 July 2017 Our paper on the synthesis of virosaine A is out. Congrats to Jon Hughes on a great piece of work 16 May 2017 New CIHR grant - “Bifunctional non-secosteroidal vitamin D analogues as novel cancer chemotherapeutics” 10 May 2017 Our paper on organocatalytic Michael reactions is out. Congrats to Florent, Adamo, Nick, Jon and Damien 8 May 2017 Welcome to Thomas Bräuer, visiting student from Konrad Tiefenbacher’s group at U. Basel 1 May 2017 Welcome to summer students - Alexandra Lacoste, Daisy He and Dean Noutsious 23 March 2017 New NSERC Engage grant with Inception Sciences - “Development of a general approach to substituted bicyclo[1.1.1]pentanes”https://bsky.app/profile/gleason-group.bsky.socialhttps://twitter.com/Gleason_Labhttp://dx.doi.org/10.1002/chem.202201418https://www.nature.com/articles/s41598-022-10740-9https://pubs.acs.org/doi/10.1021/acs.orglett.2c00444https://www.sciencedirect.com/science/article/pii/S0960894X21006685https://cdnsciencepub.com/doi/10.1139/cjc-2021-0150https://pubs.acs.org/doi/10.1021/jacs.0c08427https://pubs.acs.org/doi/10.1021/acs.orglett.9b03887https://onlinelibrary.wiley.com/doi/10.1002/anie.201911952https://pubs.acs.org/doi/10.1021/acs.orglett.9b02426https://onlinelibrary.wiley.com/doi/10.1002/ejoc.201801009https://www.sciencedirect.com/science/article/pii/S0968089618304334?via=ihubhttps://www.sciencedirect.com/science/article/pii/S0040402017312863http://www.sciencedirect.com/science/article/pii/S096007601730225Xhttp://onlinelibrary.wiley.com/doi/10.1002/anie.201706273/fullhttp://onlinelibrary.wiley.com/doi/10.1002/ejoc.201700469/fullhttps://pubs.acs.org/doi/10.1021/acs.orglett.2c00444shapeimage_1_link_0shapeimage_1_link_1shapeimage_1_link_2shapeimage_1_link_3shapeimage_1_link_4shapeimage_1_link_5shapeimage_1_link_6shapeimage_1_link_7shapeimage_1_link_8shapeimage_1_link_9shapeimage_1_link_10shapeimage_1_link_11shapeimage_1_link_12shapeimage_1_link_13shapeimage_1_link_14shapeimage_1_link_15shapeimage_1_link_16